SCHEMBL23366554

SCHEMBL23366554

CCCC/C=C(\C)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 12/20 0.37
CES1 P23141 8/20 0.37
CES2 O00748 3/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALDH1A1 P00352 2/20 0.35
PLA2G4B P0C869 1/20 0.35
MAPT P10636 1/20 0.35
PLA2G4A P47712 1/20 0.35
BLM P54132 1/20 0.35
MGLL Q99685 1/20 0.35
PLA2G4C Q9UP65 1/20 0.35
TSHR P16473 2/20 0.35
EP300 Q09472 1/20 0.34
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13517933 0.91 FAAH (0.47) FAAHCES1CES2MEN1CYP1A2
SCHEMBL27726004 0.81 FAAH (0.37) FAAHCES1CES2MEN1CYP1A2
SCHEMBL17963695 0.78 FAAH (0.38) FAAHCES1CES2MEN1CYP1A2
SCHEMBL21104977 0.78 TSHR (0.36) ALDH1A1TSHREP300
SCHEMBL27882230 0.78 TSHR (0.36) ALDH1A1TSHREP300
SCHEMBL7470757 0.75
SCHEMBL7470760 0.75
SCHEMBL7470765 0.75
SCHEMBL27453897 0.74 FAAH (0.36) FAAHCES1CES2MEN1CYP1A2
SCHEMBL27916777 0.74 FAAH (0.44) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3822245-A1 NEW PROCESS FOR THE SYNTHESIS OF 2,3,3,3-TETRAFLUOROPROPENE (1234YF) AND 2,3-DICHLORO-1,1,1-TRIFLUOROPROPANE (243DB) Fujian Yongjing Technology Co., Ltd. (CN) 2021-05-19 EP disclosed