Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17842007 | 0.86 | LTA4H (0.60) | DRD2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17858356 | 0.85 | KDM4E (0.55) | DRD2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17842398 | 0.83 | LTA4H (0.54) | DRD2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17842157 | 0.82 | KDM4E (0.53) | DRD2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23366605 | 0.81 | KDM4E (0.52) | DRD2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17858391 | 0.80 | KDM4E (0.51) | DRD2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL13698799 | 0.78 | KDM4E (0.69) | DRD2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17842078 | 0.78 | LTA4H (0.57) | DRD2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23366615 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL12464797 | 0.78 | KDM4E (0.57) | DRD2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233799-B1 | DOPAMINE D2 RECEPTOR LIGANDS | BROAD INST INC (US) | 2021-05-19 | — | — | EP | disclosed |