Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15077060 | 0.76 | CYP17A1 (0.34) | ADRA1APTGS2MAPK1 | |
| SCHEMBL25619183 | 0.73 | CYP17A1 (0.33) | ADRA1APTGS2MAPK1 | |
| SCHEMBL16502337 | 0.70 | CYP17A1 (0.35) | KDM4EADRA1A | |
| SCHEMBL22055651 | 0.70 | ACHE (0.31) | ADRA1AMAPK1 | |
| SCHEMBL30814588 | 0.70 | ESR1 (0.36) | ADRA1AMAPK1 | |
| SCHEMBL23361592 | 0.69 | FLT1 (0.35) | ADRA1AMAPTHPGDMEN1LMNA | |
| SCHEMBL2214930 | 0.68 | MAPK1 (0.38) | ADRA1AMAPTHPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL23354081 | 0.68 | FLT1 (0.34) | ADRA1AMAPTHPGDMEN1LMNA | |
| SCHEMBL16815632 | 0.67 | CYP17A1 (0.35) | ADRA1A | |
| SCHEMBL17076689 | 0.67 | CCNC (0.39) | ADRA1AMAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822268-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2021-05-19 | — | — | EP | disclosed |