Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS7 | Q9UKP4 | 11/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23384608 | 0.91 | ADAMTS7 (0.62) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL23354910 | 0.84 | ADAMTS7 (0.65) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL29874194 | 0.84 | ADAMTS7 (0.65) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL23367480 | 0.77 | ADAMTS7 (0.78) | ADAMTS7HDAC1 | |
| SCHEMBL23367363 | 0.76 | ADAMTS7 (0.52) | ADAMTS7HDAC1NPC1RAB9AP2RX7 | |
| SCHEMBL29873787 | 0.75 | ADAMTS7 (0.66) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL23354853 | 0.75 | ADAMTS7 (0.66) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL23354777 | 0.74 | ADAMTS7 (0.66) | ADAMTS7HDAC1 | |
| SCHEMBL29873810 | 0.74 | ADAMTS7 (0.66) | ADAMTS7HDAC1 | |
| SCHEMBL23354781 | 0.74 | ADAMTS7 (0.63) | ADAMTS7HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |