Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578571 | 0.83 | MEN1 (0.67) | KMT2AMEN1CYP1A2NPSR1RAB9A | |
| SCHEMBL10578566 | 0.83 | MEN1 (0.67) | KMT2AMEN1CYP1A2NPSR1RAB9A | |
| SCHEMBL27983351 | 0.81 | MEN1 (0.69) | KMT2AMEN1CYP1A2NPSR1GAA | |
| SCHEMBL23367403 | 0.79 | MEN1 (0.49) | KMT2AMEN1CYP1A2NPSR1RAB9A | |
| SCHEMBL8873014 | 0.77 | MAPT (0.50) | KMT2AMEN1CYP1A2NPSR1RAB9A | |
| SCHEMBL23367380 | 0.73 | GAA (0.63) | KMT2AMEN1CYP1A2NPSR1MAOB | |
| SCHEMBL24576668 | 0.70 | KMT2A (0.61) | KMT2AMEN1CYP1A2NPSR1RAB9A | |
| SCHEMBL2728508 | 0.70 | MEN1 (0.61) | KMT2AMEN1CYP1A2NPSR1MAPT | |
| SCHEMBL21848350 | 0.70 | MEN1 (0.61) | KMT2AMEN1CYP1A2NPSR1RAB9A | |
| SCHEMBL21848352 | 0.70 | MEN1 (0.61) | KMT2AMEN1CYP1A2NPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |