Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 4/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14135715 | 0.84 | MEN1 (0.65) | MEN1KMT2ACYP1A2NPSR1MMP1 | |
| SCHEMBL5952682 | 0.84 | MEN1 (0.65) | MEN1KMT2ACYP1A2NPSR1MMP1 | |
| SCHEMBL5952677 | 0.84 | MEN1 (0.65) | MEN1KMT2ACYP1A2NPSR1MMP1 | |
| SCHEMBL23367380 | 0.81 | GAA (0.63) | MEN1KMT2ACYP1A2NPSR1MMP1 | |
| SCHEMBL27983351 | 0.80 | MEN1 (0.69) | MEN1KMT2AP2RX7CYP1A2NPSR1 | |
| SCHEMBL23367369 | 0.79 | KMT2A (0.50) | MEN1KMT2ACYP1A2NPSR1GAA | |
| SCHEMBL20984414 | 0.78 | GAA (0.61) | MEN1KMT2AP2RX7MMP1MMP2 | |
| SCHEMBL5253044 | 0.75 | P2RX7 (0.54) | MEN1KMT2AP2RX7MMP1MMP2 | |
| SCHEMBL8873014 | 0.73 | MAPT (0.50) | MEN1KMT2ACYP1A2NPSR1GAA | |
| SCHEMBL15353151 | 0.72 | MMP1 (0.45) | MEN1KMT2AP2RX7MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |