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SCHEMBL23367673

SCHEMBL23367673

Cc1cc(C)cc(-c2cccc(-c3cc(C)cc(C)c3)c2N2/C(=C/C=C3C(=O)c4ccccc4C3=O)N(c3c(C(C)C)cccc3C(C)C)c3nc4cc(C#N)c(C#N)cc4nc32)c1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 3/20 0.33
▸ NR1H2 P55055 1/20 0.33
▸ NR1H3 Q13133 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ USP8 P40818 1/20 0.33
▸ USP7 Q93009 1/20 0.33
▸ ANPEP P15144 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23337144 0.97 USP8 (0.33) DPP4NR1H2NR1H3MEN1PKM
SCHEMBL25850989 0.87 USP8 (0.35) DPP4NR1H2NR1H3MEN1PKM
SCHEMBL23337547 0.85 DPP4 (0.34) DPP4NR1H2NR1H3MEN1KMT2A
SCHEMBL23337551 0.83 ANPEP (0.34) DPP4NR1H2NR1H3ANPEP
SCHEMBL23338738 0.83 KRAS (0.32) DPP4NR1H2NR1H3ANPEP
SCHEMBL25849595 0.82 USP8 (0.34) DPP4NR1H2NR1H3MEN1PKM
SCHEMBL23337106 0.82 ANPEP (0.33) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337546 0.81 DPP4 (0.42) DPP4NR1H2NR1H3MEN1PKM
SCHEMBL23337978 0.81 ANPEP (0.32) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337148 0.80 ANPEP (0.32) DPP4NR1H2NR1H3ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3823054-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM Corporation (JP) 2021-05-19 — — EP disclosed