SCHEMBL25850989

SCHEMBL25850989

Cc1ccc2c(c1)C(=O)/C(=C/C=C1N(c3c(C(C)C)cccc3C(C)C)c3nc4cc(C#N)c(C#N)cc4nc3N1c1c(C(C)C)cccc1C(C)C)C2=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP8 P40818 2/20 0.35
USP7 Q93009 2/20 0.35
ANPEP P15144 3/20 0.34
DPP4 P27487 3/20 0.34
ELANE P08246 1/20 0.32
KDM4E B2RXH2 4/20 0.32
ALDH1A1 P00352 3/20 0.32
HPGD P15428 3/20 0.32
MAPK1 P28482 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
TSHR P16473 2/20 0.32
MAPT P10636 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
MEN1 O00255 1/20 0.31
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849837 0.89 ANPEP (0.37) ANPEPDPP4ELANEALDH1A1MAPT
SCHEMBL25849822 0.88 ELANE (0.39) ANPEPDPP4ELANEKDM4EALDH1A1
SCHEMBL25849833 0.87 ANPEP (0.36) ANPEPDPP4ELANEMAPTNR1H2
SCHEMBL25849832 0.87 ANPEP (0.36) ANPEPDPP4ELANEMAPTNR1H2
SCHEMBL23367673 0.87 DPP4 (0.33) USP8USP7ANPEPDPP4NR1H2
SCHEMBL23337144 0.86 USP8 (0.33) USP8USP7ANPEPDPP4NR1H2
SCHEMBL25849595 0.85 USP8 (0.34) USP8USP7ANPEPDPP4NR1H2
SCHEMBL25849823 0.84 ANPEP (0.33) USP8USP7ANPEPDPP4ELANE
SCHEMBL23337886 0.83 MAPT (0.40) ANPEPDPP4ELANEKDM4EALDH1A1
SCHEMBL25849838 0.83 TP53 (0.40) ANPEPDPP4KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed