Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2182370 | 0.86 | KMT2A (0.61) | KMT2AMEN1TDP1PARP1RXFP1 | |
| SCHEMBL30758600 | 0.82 | HPGD (0.70) | KMT2AMEN1TDP1PARP1LMNA | |
| SCHEMBL11587152 | 0.82 | HPGD (0.70) | KMT2AMEN1TDP1PARP1LMNA | |
| SCHEMBL23367899 | 0.82 | HPGD (0.61) | KMT2APARP1LMNAHTTKDM4E | |
| SCHEMBL15528435 | 0.79 | TSHR (0.69) | KMT2AMEN1TDP1LMNAHTT | |
| SCHEMBL4062158 | 0.79 | KMT2A (0.60) | KMT2AMEN1TDP1PARP1TP53 | |
| SCHEMBL15541786 | 0.79 | HTT (0.64) | KMT2AMEN1TDP1PARP1RXFP1 | |
| SCHEMBL16919734 | 0.79 | CYP1A2 (0.77) | KMT2AMEN1TDP1PARP1KDM4E | |
| SCHEMBL29168832 | 0.79 | KMT2A (0.64) | KMT2AMEN1TDP1PARP1RXFP1 | |
| SCHEMBL20385167 | 0.79 | HDAC1 (0.61) | KMT2AMEN1TDP1PARP1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822253-A1 | METHOD FOR PREPARING PROPANEDINITRILE OXIME ETHER COMPOUND AND INTERMEDIATE COMPOUND | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2021-05-19 | — | — | EP | disclosed |