Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PLK1 | P53350 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2344909 | 0.84 | GAA (0.71) | KMT2AGAAPLK1BRD4KAT2B | |
| SCHEMBL24616780 | 0.80 | PLK1 (0.49) | KMT2AMEN1TDP1GAAPLK1 | |
| SCHEMBL27583795 | 0.80 | MEN1 (0.62) | KMT2AMEN1TDP1GAAPARP1 | |
| SCHEMBL28415607 | 0.79 | MEN1 (0.56) | KMT2AMEN1TDP1PARP1POLB | |
| SCHEMBL23367889 | 0.79 | KMT2A (0.61) | KMT2AMEN1TDP1GAAPARP1 | |
| Dimethylamine SCHEMBL1168842 | 0.78 | KMT2A (0.55) | KMT2AMEN1TDP1GAAPOLB | |
| SCHEMBL2293802 | 0.78 | MEN1 (0.60) | KMT2AMEN1TDP1GAAPARP1 | |
| SCHEMBL6958929 | 0.78 | MEN1 (0.60) | KMT2AMEN1TDP1GAAPARP1 | |
| SCHEMBL4352870 | 0.78 | KMT2A (0.55) | KMT2AMEN1TDP1BRD4 | |
| SCHEMBL6740430 | 0.78 | MEN1 (0.55) | KMT2AMEN1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113548948-B | Preparation method of methyl octabromoether | 宿迁联盛科技股份有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-120004754-A | Preparation method of high-purity N-methyl halogenated benzamide | 福州大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-116535344-B | Phthalimide preparation method of class compound | 华南理工大学 | 2024-10-01 | — | — | CN | disclosed |
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | VALO HEALTH, INC. | 2023-11-02 | — | — | US | disclosed |
| EP-3480187-B1 | METHOD FOR PREPARING INDENOISOQUINOLINE DERIVATIVES | UNIV NAT TAIWAN NORMAL (TW) | 2023-10-04 | — | — | EP | disclosed |
| CN-116535344-A | Preparation method of phthalimide compound | 华南理工大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-113548948-B | Preparation method of methyl octabromoether | 宿迁联盛科技股份有限公司 | 2023-04-14 | — | — | CN | disclosed |
| US-11274106-B2 | Topoisomerase inhibitors with antibacterial and anticancer activity | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-03-15 | — | — | US | disclosed |
| WO-2021028935-A1 | HETEROCYCLIC COMPOUNDS, AND THEIR USE AS ALLOSTERIC MODULATORS OF 5-HYDROXYTRYPTAMINE 2C RECEPTOR (5-HT2CR) | DR REDDY'S INSTITUTE OF LIFE SCIENCES (IN) | 2021-02-18 | — | — | WO | disclosed |
| WO-2020219650-A1 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-10-29 | — | — | WO | disclosed |
| EP-1893596-A2 | BENZOÝB¨FURANE AND BENZOÝB¨THIOPHENE DERIVATIVES | H.Lundbeck A/S (DK) | 2008-03-05 | — | — | EP | disclosed |
| US-20070276016-A1 | BENZO[1,2,5]THIADIAZOLE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-29 | — | — | US | disclosed |
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |
| WO-2007023395-A2 | BENZO[B]FURANE AND BENZO[B]THIOPHENE DERIVATIVES | H. LUNDBECK A/S (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2006-12-21 | — | — | US | disclosed |
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0859757-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | Farmak A.S. (CZ) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017325-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | FARMAK A.S. (CZ) | 1997-05-15 | — | — | WO | disclosed |
| US-4279887-A | RADIOACTIVE SCANNING | MEDI-PHYSICS, INC. (US) | 1981-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | CYP1B1, TBCB, CYP4B1 | KMT2A 3617/4885MEN1 2561/4885TDP1 1262/4885 |
| US-20070276016-A1 | BENZO[1,2,5]THIADIAZOLE COMPOUNDS | CCKBR, CCKAR, GIPR | KMT2A 3053/4885MEN1 2768/4885TDP1 3185/4885 |
| US-11274106-B2 | Topoisomerase inhibitors with antibacterial and anticancer activity | TOP2A, TOP1, TOP2B | KMT2A 1764/4885MEN1 1730/4885TDP1 37/4885 |
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, NNMT, NQO1 | KMT2A 1615/4885MEN1 582/4885TDP1 3947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.