Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.71 |
| ▸ | HPGDS | O60760 | 2/20 | 0.58 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
| ▸ | STAMBP | O95630 | 1/20 | 0.55 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362497 | 1.00 | MGAM (0.71) | MGAMHPGDSCHEK2PSMD14STAMBP | |
| Hydrochloric Acid SCHEMBL5311903 | 0.98 | MGAM (0.69) | MGAMHPGDSCHEK2PSMD14STAMBP | |
| Hydrochloric Acid SCHEMBL28841803 | 0.98 | MGAM (0.69) | MGAMHPGDSCHEK2PSMD14STAMBP | |
| Hydrochloric Acid SCHEMBL28129921 | 0.98 | MGAM (0.69) | MGAMHPGDSCHEK2PSMD14STAMBP | |
| Fluoride SCHEMBL28234122 | 0.98 | MGAM (0.69) | MGAMHPGDSCHEK2PSMD14STAMBP | |
| SCHEMBL27583240 | 0.98 | MGAM (0.69) | MGAMHPGDSCHEK2PSMD14STAMBP | |
| Quinoline SCHEMBL28179581 | 0.92 | MGAM (0.61) | MGAMHPGDSCHEK2PSMD14STAMBP | |
| Trifluoroacetic Acid SCHEMBL8360271 | 0.89 | MGAM (0.62) | MGAMHPGDSCHEK2PSMD14STAMBP | |
| Isoquinoline SCHEMBL28230213 | 0.88 | MGAM (0.56) | MGAMHPGDSCHEK2PSMD14STAMBP | |
| Urea SCHEMBL27348385 | 0.86 | MGAM (0.90) | MGAMHPGDSCHEK2PSMD14CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119998297-A | Crystalline forms of (3 s,7s,10r,13 r) -13-benzyl-20-fluoro-7-isobutyl-N- (2- (3-methoxy-1, 2, 4-oxadiazol-5-yl) ethyl) -6, 9-dimethyl-1,5,8,11-tetraoxo-10- (2, 2-trifluoroethyl) -1,2,3,4,5,6,7,8,9,10,11,12,13,14-decatetrahydro- [1] oxa [4,7,10,14] tetraazaheptadecao [16,17-f ] quinoline-3-carboxamide | 爱杜西亚药品有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119907667-A | Combination of macrocyclic CFTR modulators with CFTR corrector and/or CFTR potentiator | 爱杜西亚药品有限公司 | 2025-04-29 | — | — | CN | claimed |
| EP-4525858-A1 | METHODS OF TREATMENT FOR CYSTIC FIBROSIS | Vertex Pharmaceuticals Incorporated (US) | 2025-03-26 | — | — | EP | claimed |
| EP-4472635-A1 | METHODS OF TREATMENT FOR CYSTIC FIBROSIS | Vertex Pharmaceuticals Incorporated (US) | 2024-12-11 | — | — | EP | claimed |
| EP-4422402-A1 | FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL | Syngenta Crop Protection AG (CH) | 2024-09-04 | — | — | EP | claimed |
| EP-4384016-A1 | ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE | Bayer Aktiengesellschaft (DE) | 2024-06-19 | — | — | EP | claimed |
| EP-4377305-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | BenevolentAI Cambridge Limited (GB) | 2024-06-05 | — | — | EP | claimed |
| CN-117751107-A | Organic pyridine-pyrazole compounds and uses thereof | 博善人工智能剑桥有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117603219-A | P-glycoprotein inhibitor and preparation method and application thereof | 浙江大学 | 2024-02-27 | — | — | CN | claimed |
| CN-110869363-B | 5-membered and bicyclic heterocyclic amides as ROCK inhibitors | 百时美施贵宝公司 | 2024-01-05 | — | — | CN | claimed |
| WO-1995024196-A1 | NEW USE OF QUINOLINE-3-CARBOXAMIDE COMPOUNDS | PHARMACIA & UPJOHN AB (SE) | 1995-09-14 | — | — | WO | claimed |
| WO-1995003051-A1 | USE OF QUINOLINE-3-CARBOXAMIDE COMPOUNDS FOR INHIBITING THE PRODUCTION OF TUMOUR NECROSIS FACTOR (TNF) AND/OR FOR THE TREATMENT OF SEPTIC SHOCK | PHARMACIA AB (SE) | 1995-02-02 | — | — | WO | claimed |
| EP-0634931-A1 | THE USE OF QUINOLINE-3-CARBOXAMIDE COMPOUNDS FOR TREATMENT OF DIABETES | Pharmacia & Upjohn Aktiebolag (SE) | 1995-01-25 | — | — | EP | claimed |
| WO-1993019756-A9 | THE USE OF QUINOLINE-3-CARBOXAMIDE COMPOUNDS FOR TREATMENT OF DIABETES | — | 1994-10-27 | — | — | WO | claimed |
| EP-0607282-A1 | NEW USE OF SUBSTITUTED QUINOLINE CARBOXAMIDE | Pharmacia & Upjohn Aktiebolag (SE) | 1994-07-27 | — | — | EP | claimed |
| WO-1993019756-A1 | THE USE OF QUINOLINE-3-CARBOXAMIDE COMPOUNDS FOR TREATMENT OF DIABETES | KABI PHARMACIA AB (SE) | 1993-10-14 | — | — | WO | claimed |
| WO-1993006829-A1 | NEW USE OF SUBSTITUTED QUINOLINE CARBOXAMIDE | KABI PHARMACIA AB (SE) | 1993-04-15 | — | — | WO | claimed |
| US-4845105-A | 4-OH-quinoline carboxylic acid amides having analgesic and anti-inflammatory activity | ROUSSEL UCLAF (FR) | 1989-07-04 | — | — | US | claimed |
| US-4450167-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | ROUSSEL UCLAF (FR) | 1984-05-22 | — | — | US | claimed |
| US-4299831-A | 2-Trifluoromethyl-3-quinoline carboxamides, analgesic and anti-inflammatory compositions and methods employing them | ROUSSEL UCLAF (FR) | 1981-11-10 | — | — | US | claimed |