Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.62 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 2/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.47 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | STAMBP | O95630 | 1/20 | 0.47 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362497 | 0.89 | MGAM (0.71) | MGAMCFTRHPGDSCHEK2TOP2A | |
| SCHEMBL23372 | 0.89 | MGAM (0.71) | MGAMCFTRHPGDSCHEK2TOP2A | |
| Trifluoroacetic Acid SCHEMBL9693430 | 0.88 | MGAM (0.81) | MGAMCFTRHPGDSTOP2ATOP2B | |
| Fluoride SCHEMBL28234122 | 0.88 | MGAM (0.69) | MGAMCFTRHPGDSCHEK2TOP2A | |
| Hydrochloric Acid SCHEMBL5311903 | 0.88 | MGAM (0.69) | MGAMCFTRHPGDSCHEK2TOP2A | |
| Hydrochloric Acid SCHEMBL28129921 | 0.88 | MGAM (0.69) | MGAMCFTRHPGDSCHEK2TOP2A | |
| SCHEMBL27583240 | 0.88 | MGAM (0.69) | MGAMCFTRHPGDSCHEK2TOP2A | |
| Hydrochloric Acid SCHEMBL28841803 | 0.88 | MGAM (0.69) | MGAMCFTRHPGDSCHEK2TOP2A | |
| SCHEMBL30831204 | 0.84 | MGAM (0.65) | MGAMCFTRHPGDSTOP2ATOP2B | |
| Trifluoroacetic Acid SCHEMBL30684640 | 0.82 | MGAM (0.53) | MGAMCFTRTOP2ATOP2BBCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940562-A | Acetamido-phenylbenzamide derivatives and methods of use thereof | 希华医药有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-110049979-A | BROMODOMAIN INHIBITORS | 艾伯维公司 | 2019-07-23 | — | — | CN | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |