Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23375452 | 1.00 | KDM1A (0.55) | KDM1ACYP2D6CHRM4MEN1KMT2A | |
| SCHEMBL28954166 | 0.94 | KDM1A (0.53) | KDM1ACYP2D6CHRM4MEN1KMT2A | |
| SCHEMBL23778367 | 0.89 | CYP2D6 (0.52) | KDM1ACYP2D6CHRM4MEN1KMT2A | |
| SCHEMBL23778311 | 0.89 | CYP2D6 (0.52) | KDM1ACYP2D6CHRM4MEN1KMT2A | |
| SCHEMBL20066070 | 0.85 | CYP2D6 (0.46) | KDM1ACYP2D6CHRM4MEN1KMT2A | |
| SCHEMBL23778309 | 0.77 | CYP2D6 (0.52) | KDM1ACYP2D6CHRM4MEN1KMT2A | |
| SCHEMBL23778364 | 0.77 | CYP2D6 (0.52) | KDM1ACYP2D6CHRM4MEN1KMT2A | |
| SCHEMBL23778221 | 0.77 | CYP2D6 (0.48) | KDM1ACYP2D6CHRM4MEN1KMT2A | |
| SCHEMBL23778247 | 0.77 | CYP2D6 (0.48) | KDM1ACYP2D6CHRM4MEN1KMT2A | |
| SCHEMBL20073962 | 0.76 | CYP2D6 (0.51) | KDM1ACYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014880-B2 | Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2021-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11014880-B2 | Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists | CHRM1, CHRM2, CHRM4 | KDM1A 1427/4885CYP2D6 261/4885CHRM4 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.