SCHEMBL28954166

SCHEMBL28954166

N#CC1(c2ccccc2)CCC(N2CCC(CNC(=O)O)CC2)CC1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.53
CHRM4 P08173 1/20 0.51
CYP2D6 P10635 1/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ADRA1D P25100 6/20 0.44
ADRA1A P35348 6/20 0.44
ADRA1B P35368 5/20 0.44
BDKRB1 P46663 1/20 0.43
CCR1 P32246 1/20 0.43
OPRM1 P35372 1/20 0.42
OPRD1 P41143 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23375451 0.94 KDM1A (0.55) KDM1ACHRM4CYP2D6MEN1KMT2A
SCHEMBL23375452 0.94 KDM1A (0.55) KDM1ACHRM4CYP2D6MEN1KMT2A
SCHEMBL20066070 0.90 CYP2D6 (0.46) KDM1ACHRM4CYP2D6MEN1KMT2A
SCHEMBL23778367 0.84 CYP2D6 (0.52) KDM1ACHRM4CYP2D6MEN1KMT2A
SCHEMBL23778311 0.84 CYP2D6 (0.52) KDM1ACHRM4CYP2D6MEN1KMT2A
SCHEMBL23778247 0.79 CYP2D6 (0.48) KDM1ACHRM4CYP2D6MEN1KMT2A
SCHEMBL23778221 0.79 CYP2D6 (0.48) KDM1ACHRM4CYP2D6MEN1KMT2A
SCHEMBL23798654 0.78 OPRL1 (0.56) KDM1ACYP2D6MEN1KMT2ACCR1
SCHEMBL23778458 0.77 CYP2D6 (0.53) KDM1ACHRM4CYP2D6MEN1KMT2A
SCHEMBL9435664 0.77 OPRL1 (0.58) KDM1ACYP2D6CCR1OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109996792-B Heterocyclic compounds having activity as modulators of muscarinic M1 and/or M4 receptors in the treatment of CNS diseases and pain 赫普泰雅治疗有限公司 2023-02-17 CN claimed