Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18916791 | 0.85 | CYP1A2 (0.48) | GABRR1CYP1A2ALDH1A1BLMACE2 | |
| SCHEMBL24872517 | 0.83 | CYP1A2 (0.47) | GABRR1CYP1A2ALDH1A1BLMACE2 | |
| SCHEMBL1855094 | 0.82 | CYP1A2 (0.50) | GABRR1CYP1A2ALDH1A1BLMSMN1; SMN2 | |
| SCHEMBL24872440 | 0.81 | CYP1A2 (0.45) | GABRR1CYP1A2ALDH1A1BLM | |
| Hydrochloric Acid SCHEMBL1859894 | 0.81 | CYP1A2 (0.48) | GABRR1CYP1A2ALDH1A1BLMSMN1; SMN2 | |
| SCHEMBL1852896 | 0.81 | CYP1A2 (0.48) | GABRR1CYP1A2ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1853458 | 0.81 | CYP1A2 (0.48) | GABRR1CYP1A2ALDH1A1BLMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1856681 | 0.79 | CYP1A2 (0.47) | GABRR1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL25660594 | 0.78 | ALDH1A1 (0.66) | CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL27438939 | 0.78 | CHRM5 (0.46) | GABRR1CYP1A2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202874-A1 | FURIN INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS | BP ASSET V, INC. (US) | 2021-10-07 | — | — | WO | disclosed |
| WO-2021097009-A1 | SMALL MOLECULE FURIN INHIBITORS FOR TREATING INFECTIOUS DISEASES | BP ASSET V, INC. (US) | 2021-05-20 | — | — | WO | disclosed |
| WO-2021097008-A1 | USE OF PYRIDYLOXYPYRIDINES FOR TREATING INFECTIOUS DISEASES | BP ASSET V, INC. (US) | 2021-05-20 | — | — | WO | disclosed |