Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.31 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.31 |
| ▸ | GRB2 | P62993 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4143714 | 0.78 | IDO1 (0.34) | — | |
| SCHEMBL31451471 | 0.78 | MEN1 (0.32) | — | |
| SCHEMBL32811 | 0.76 | KDM4E (0.35) | — | |
| SCHEMBL29519855 | 0.75 | MAP4K4 (0.36) | SCN9A | |
| SCHEMBL27754726 | 0.75 | HSP90AA1 (0.42) | SCN9AGRB2 | |
| SCHEMBL2420410 | 0.74 | — | — | |
| SCHEMBL30936047 | 0.74 | IDH1 (0.39) | — | |
| SCHEMBL28408851 | 0.73 | KDM4E (0.33) | — | |
| SCHEMBL16784615 | 0.72 | HSP90AA1 (0.48) | — | |
| SCHEMBL2531557 | 0.70 | DYRK1A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204411-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | Nalo Therapeutics (US) | 2023-07-05 | — | — | EP | disclosed |
| EP-3999064-A1 | INHIBITORS OF TYROSINE KINASE | Bridgene Biosciences, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |
| WO-2022046861-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2022-03-03 | — | — | WO | disclosed |
| EP-2152702-B1 | AMINO-THIAZOLYL- PYRIMIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2011-08-24 | — | — | EP | disclosed |
| CN-1250735-C | Method for production of non-proteinogen L-amino acid by fermentation | ELECTRO CHEMICAL IND GMBH INTE (DE) | 2006-04-12 | — | — | CN | disclosed |
| CN-1344801-A | Method for production of non-proteinogen L-amino acid by fermentation | ELECTRO CHEMICAL IND GMBH INTE (DE) | 2002-04-17 | — | — | CN | disclosed |