SCHEMBL32811

SCHEMBL32811

c1cnc(-c2cc[nH]n2)nc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.35
LMNA P02545 3/20 0.35
CCR1 P32246 2/20 0.35
CCR5 P51681 2/20 0.35
CCR8 P51685 2/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
METAP1 P53582 1/20 0.35
BLM P54132 1/20 0.35
HIF1A Q16665 1/20 0.35
DOHH Q9BU89 1/20 0.35
P4HTM Q9NXG6 1/20 0.35
TDP1 Q9NUW8 3/20 0.34
TP53 P04637 3/20 0.34
CLK4 Q9HAZ1 2/20 0.34
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
L3MBTL1 Q9Y468 4/20 0.34
ALOX15 P16050 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL27737389 0.88 CLK4 (0.32) KDM4ELMNACYP1A2POLBTDP1
Quinoline SCHEMBL27874793 0.84 ALDH1A1 (0.57) KDM4ECYP1A2POLBTDP1TP53
SCHEMBL18097682 0.79 CHRNB2 (0.33) HTT
SCHEMBL29429423 0.77 KDM4E (0.61) KDM4ELMNACCR1CCR5CCR8
SCHEMBL252441 0.77 KDM4E (0.61) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28408851 0.77 KDM4E (0.33) KDM4ETDP1
SCHEMBL17476685 0.77 TP53 (0.33) TP53
SCHEMBL1673128 0.76
SCHEMBL28423686 0.76 METAP2 (0.34) KDM4EMETAP2DYRK1A
SCHEMBL27967128 0.76 KDM4E (0.58) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 697 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025110033-A1 COSMETIC 株式会社 資生堂 2025-05-30 WO claimed
US-20240358624-A1 APPLICATION TYPE BODY-CORRECTING-FILM FORMING AGENT SHISEIDO COMPANY, LTD. (JP) 2024-10-31 US claimed
WO-2024214568-A1 WATER-BASED COSMETIC 株式会社 資生堂 2024-10-17 WO claimed
US-20240293300-A1 SKIN PENETRATION COSMETIC MATERIAL, AND SKIN PENETRATION COSMETIC MATERIAL PRODUCTION METHOD SHISEIDO COMPANY, LTD. (JP) 2024-09-05 US claimed
CN-118234469-A Composition and method for producing the same 株式会社资生堂 2024-06-21 CN claimed
CN-117835973-A Coating type body correction film forming agent 株式会社资生堂 2024-04-05 CN claimed
CN-117835966-A Method for promoting skin penetration of water-soluble pharmaceutical agent 株式会社资生堂 2024-04-05 CN claimed
CN-117545456-A Cosmetic for skin permeation and method for producing cosmetic for skin permeation 株式会社资生堂 2024-02-09 CN claimed
CN-117545457-A Cosmetic for skin penetration 株式会社资生堂 2024-02-09 CN claimed
WO-2023205507-A1 ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE ESSA PHARMA INC. (CA) 2023-10-26 WO claimed
CN-1492864-A Pyrazolyl pyrimidines �ݶ�ũ�����ѧ�ɷݹ�˾ 2004-04-28 CN claimed
EP-1363905-A1 PYRAZOLYL PYRIMIDINES Bayer CropScience AG (DE) 2003-11-26 EP claimed
WO-2002068413-A1 PYRAZOLYL PYRIMIDINES BAYER CROPSCIENCE AG (DE) 2002-09-06 WO claimed
CN-1296812-A Composition for oxidation dyeing keratoprotein fibre and method for dyeing using said composition OREAL (FR) 2001-05-30 CN claimed
CN-1241137-A Composition for the oxidation dyeing of keratin fibres and dyeing process using this composition OREAL (FR) 2000-01-12 CN claimed
US-5599582-A Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-02-04 US claimed
US-5569739-A Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-10-29 US claimed
US-5326643-A Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-07-05 US claimed
EP-0536606-A2 An adhesive layer in multilevel packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1993-04-14 EP claimed
US-4405743-A AGRICULTURAL FUNGICIDES HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1983-09-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358624-A1 APPLICATION TYPE BODY-CORRECTING-FILM FORMING AGENT CUTA, DSG1, KRT18 KDM4E 3532/4885LMNA 2286/4885CCR1 4626/4885
US-20240293300-A1 SKIN PENETRATION COSMETIC MATERIAL, AND SKIN PENETRATION COSMETIC MATERIAL PRODUCTION METHOD CUTA, SLC6A12, DSG1 KDM4E 4508/4885LMNA 354/4885CCR1 2799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.