SCHEMBL23376901

SCHEMBL23376901

CC[C@@H](C)c1cccc(Cl)n1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
IDH1 O75874 9/20 0.37
IDH2 P48735 8/20 0.37
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.36
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR3A P46098 1/20 0.33
HTR3D Q70Z44 1/20 0.33
HTR3C Q8WXA8 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12891649 1.00 L3MBTL1 (0.41) L3MBTL1IDH1IDH2TSHRCYP3A4
SCHEMBL3631871 0.85 TSHR (0.41) L3MBTL1TSHRCYP3A4ALDH1A1GAA
SCHEMBL18855225 0.85 L3MBTL1 (0.39) L3MBTL1IDH1IDH2TSHRCYP3A4
SCHEMBL1986238 0.82 TAAR1 (0.41) L3MBTL1IDH1IDH2TSHRCYP3A4
SCHEMBL18557494 0.82 L3MBTL1 (0.42) L3MBTL1IDH1IDH2TSHRCYP3A4
SCHEMBL12041515 0.81 L3MBTL1 (0.39) L3MBTL1IDH1IDH2TSHRCYP3A4
SCHEMBL23084238 0.81 L3MBTL1 (0.39) L3MBTL1IDH1IDH2TSHRCYP3A4
SCHEMBL21444835 0.79 TSHR (0.38) TSHRALDH1A1HDAC4HDAC2HDAC8
SCHEMBL22883935 0.79 TSHR (0.38) TSHRALDH1A1HDAC4HDAC2HDAC8
SCHEMBL18869118 0.79 KCNH2 (0.40) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021097139-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL RECURIUM IP HOLDINGS, LLC (US) 2021-05-20 WO disclosed