Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 7/20 | 0.33 |
| ▸ | NCF1 | P14598 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 5/20 | 0.31 |
| ▸ | HTR1B | P28222 | 5/20 | 0.31 |
| ▸ | OGA | O60502 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23377819 | 0.89 | — | — | |
| SCHEMBL23377485 | 0.86 | BTK (0.30) | OGA | |
| SCHEMBL23377619 | 0.85 | OGA (0.34) | OGA | |
| SCHEMBL23377793 | 0.84 | GRIN1 (0.32) | OGA | |
| SCHEMBL23377474 | 0.81 | OGA (0.33) | OGA | |
| SCHEMBL23377477 | 0.81 | OGA (0.34) | OGA | |
| SCHEMBL23377478 | 0.81 | OGA (0.34) | OGA | |
| SCHEMBL23377610 | 0.81 | OGA (0.32) | OGA | |
| SCHEMBL23377815 | 0.81 | OGA (0.32) | OGA | |
| SCHEMBL23377618 | 0.81 | OGA (0.34) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021094312-A1 | PYRROLIDINE AND BICYCLOHETEROARYL CONTAINING OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-05-20 | — | — | WO | disclosed |