Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23366889 | 0.83 | KMT2A (0.45) | ALDH1A1EPHX1TDP1TSHRKMT2A | |
| SCHEMBL23371333 | 0.83 | OPRK1 (0.35) | PIK3CD | |
| SCHEMBL3091689 | 0.81 | EPHX2 (0.42) | EPHX1HSD17B10EPHX2KMT2A | |
| SCHEMBL23354550 | 0.79 | HDAC3 (0.31) | HTR1ADRD2DRD4TSHR | |
| SCHEMBL3594828 | 0.76 | GLA (0.39) | HTR1ADRD2DRD4GSK3BHSD17B10 | |
| SCHEMBL29873938 | 0.74 | KMT2A (0.43) | ALDH1A1DRD2EPHX1TDP1TSHR | |
| SCHEMBL23367237 | 0.74 | KMT2A (0.43) | ALDH1A1DRD2EPHX1TDP1TSHR | |
| SCHEMBL22312533 | 0.74 | NPC1 (0.42) | ALDH1A1EPHX1TDP1EPHX2KMT2A | |
| SCHEMBL30724425 | 0.74 | PIK3CD (0.34) | TSHRPIK3CDHPGDHTT | |
| SCHEMBL16861617 | 0.73 | GSK3B (0.38) | GSK3BTDP1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021094434-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-20 | — | — | WO | disclosed |