⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23384898 | 0.95 | — | — | |
| SCHEMBL23367311 | 0.84 | — | — | |
| SCHEMBL23745302 | 0.71 | ADAMTS5 (0.35) | — | |
| SCHEMBL31676816 | 0.70 | ADAMTS5 (0.39) | — | |
| SCHEMBL23354448 | 0.70 | ADAMTS5 (0.39) | — | |
| Hydrochloric Acid SCHEMBL23354761 | 0.69 | ADAMTS5 (0.38) | — | |
| SCHEMBL23366883 | 0.67 | GAA (0.40) | — | |
| Hydrochloric Acid SCHEMBL23354153 | 0.66 | GAA (0.39) | — | |
| SCHEMBL23367186 | 0.66 | ADAMTS5 (0.40) | — | |
| Hydrochloric Acid SCHEMBL31676812 | 0.66 | GAA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021094434-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-20 | — | — | WO | disclosed |