Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.92 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.92 |
| ▸ | OSBP | P22059 | 6/20 | 0.82 |
| ▸ | RORC | P51449 | 5/20 | 0.82 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.82 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.82 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.81 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.78 |
| ▸ | CRYAB | P02511 | 1/20 | 0.78 |
| ▸ | HMGCR | P04035 | 1/20 | 0.78 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.78 |
| ▸ | ITGAV | P06756 | 1/20 | 0.78 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.78 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.78 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.77 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.73 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cholesterol SCHEMBL21632297 | 0.96 | OSBP (0.89) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| Cholesterol SCHEMBL28238054 | 0.96 | OSBP (0.89) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL17467018 | 0.96 | GRIN1 (1.00) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL14770959 | 0.96 | GRIN1 (1.00) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL14771078 | 0.96 | GRIN1 (1.00) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| Cholesterol SCHEMBL27935905 | 0.95 | OSBP (0.91) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL21231086 | 0.92 | OSBP (0.96) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| Octacosanol SCHEMBL28595297 | 0.92 | OSBP (0.84) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| Cholesterol SCHEMBL27873562 | 0.92 | OSBP (0.84) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| Cholesterol SCHEMBL27611626 | 0.92 | OSBP (0.84) | GRIN1GRIN2AOSBPRORCOSBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210145848-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS INC (US) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210145848-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | NR1H3, NR1H2, HSD17B7 | GRIN1 1881/4885GRIN2A 3308/4885OSBP 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.