Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.44 |
| ▸ | CA1 | P00915 | 10/20 | 0.44 |
| ▸ | CA2 | P00918 | 10/20 | 0.44 |
| ▸ | CA4 | P22748 | 10/20 | 0.44 |
| ▸ | CA7 | P43166 | 10/20 | 0.44 |
| ▸ | CA9 | Q16790 | 10/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.44 |
| ▸ | CCNC | P24863 | 6/20 | 0.43 |
| ▸ | CDK8 | P49336 | 6/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23387187 | 1.00 | CA12 (0.44) | CA12CA1CA2CA4CA7 | |
| SCHEMBL29689582 | 0.84 | JAK3 (0.52) | TRPV1 | |
| SCHEMBL22499791 | 0.84 | JAK3 (0.52) | TRPV1 | |
| SCHEMBL21625645 | 0.82 | SIGMAR1 (0.51) | CA12CA1CA2CA4CA7 | |
| SCHEMBL21625644 | 0.82 | SIGMAR1 (0.51) | CA12CA1CA2CA4CA7 | |
| SCHEMBL23387371 | 0.79 | CA12 (0.52) | CA12CA1CA2CA4CA7 | |
| SCHEMBL23387372 | 0.79 | CA12 (0.52) | CA12CA1CA2CA4CA7 | |
| SCHEMBL23387271 | 0.77 | CCNC (0.63) | CA12CA1CA2CA4CA7 | |
| SCHEMBL23387275 | 0.77 | CCNC (0.63) | CA12CA1CA2CA4CA7 | |
| SCHEMBL23387323 | 0.77 | CCNC (0.63) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825303-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Nippon Chemiphar Co., Ltd. (JP) | 2021-05-26 | — | — | EP | disclosed |