Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 4/20 | 0.35 |
| ▸ | NPY4R | P50391 | 6/20 | 0.34 |
| ▸ | NPY1R | P25929 | 4/20 | 0.34 |
| ▸ | NPY2R | P49146 | 3/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21103418 | 0.93 | SIRT5 (0.36) | SIRT5NOD1C3AR1FURINNPY4R | |
| SCHEMBL15499691 | 0.93 | SIRT5 (0.36) | SIRT5NOD1C3AR1FURINNPY4R | |
| SCHEMBL20375659 | 0.93 | SIRT5 (0.36) | SIRT5NOD1C3AR1FURINNPY4R | |
| SCHEMBL20375788 | 0.93 | SIRT5 (0.36) | SIRT5NOD1C3AR1FURINNPY4R | |
| SCHEMBL18661755 | 0.93 | SIRT5 (0.36) | SIRT5NOD1C3AR1FURINNPY4R | |
| SCHEMBL16091799 | 0.93 | SIRT5 (0.36) | SIRT5NOD1C3AR1FURINNPY4R | |
| SCHEMBL20795891 | 0.90 | FURIN (0.36) | SIRT5C3AR1FURINNPY4RNPY1R | |
| SCHEMBL21915057 | 0.90 | C3AR1 (0.34) | SIRT5C3AR1FURINSMN1; SMN2LMNA | |
| SCHEMBL24490420 | 0.90 | C3AR1 (0.34) | SIRT5C3AR1FURINSMN1; SMN2LMNA | |
| SCHEMBL22001947 | 0.90 | C3AR1 (0.34) | SIRT5C3AR1FURINSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250237-B1 | HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY | SUTRO BIOPHARMA INC (US) | 2021-05-26 | — | — | EP | disclosed |