Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23395485 | 0.90 | S1PR1 (0.34) | THRBS1PR1S1PR3PTPN1ALOX5 | |
| SCHEMBL23893409 | 0.90 | THRB (0.41) | THRBS1PR1S1PR3ALOX5PTGES | |
| SCHEMBL23893406 | 0.89 | S1PR1 (0.32) | THRBS1PR1S1PR3PTPN1ALOX5 | |
| SCHEMBL23395617 | 0.89 | THRB (0.42) | THRBS1PR1S1PR3ALOX5PTGES | |
| SCHEMBL23395501 | 0.87 | THRB (0.35) | THRB | |
| SCHEMBL23893521 | 0.87 | S1PR1 (0.36) | S1PR1S1PR3PTPN1ALOX5PTGES | |
| SCHEMBL23893415 | 0.86 | S1PR1 (0.32) | S1PR1S1PR3PTPN1REN | |
| SCHEMBL25896059 | 0.86 | THRB (0.38) | THRBS1PR1S1PR3ALOX5THRA | |
| SCHEMBL23395568 | 0.85 | THRB (0.34) | THRBTHRA | |
| SCHEMBL26291499 | 0.84 | THRB (0.44) | THRBS1PR1S1PR3PTPN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |
| EP-3583092-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-05-26 | — | — | EP | disclosed |