Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23395485 | 0.92 | S1PR1 (0.34) | PTPN1S1PR1ALOX5PTGESS1PR3 | |
| SCHEMBL23395486 | 0.89 | S1PR1 (0.34) | S1PR1ALOX5PPARAPTGESS1PR3 | |
| SCHEMBL23893440 | 0.88 | PTPN1 (0.42) | PTPN1S1PR1ALOX5PPARGPPARA | |
| SCHEMBL23395492 | 0.86 | ALOX5 (0.38) | PTPN1S1PR1ALOX5PPARGPPARA | |
| SCHEMBL23395600 | 0.85 | ALOX5 (0.38) | PTPN1ALOX5PPARAPTGES | |
| SCHEMBL23395533 | 0.83 | PPARG (0.36) | PPARGPPARATHRB | |
| SCHEMBL25896330 | 0.83 | ALOX5 (0.33) | S1PR1ALOX5S1PR3MAOAMAOB | |
| SCHEMBL26291483 | 0.82 | S1PR1 (0.48) | PTPN1S1PR1ALOX5PPARGPPARA | |
| SCHEMBL23395491 | 0.81 | ALOX5 (0.39) | S1PR1ALOX5PTGESS1PR3 | |
| SCHEMBL25896594 | 0.81 | SLC10A1 (0.33) | S1PR1S1PR3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-08-02 | — | — | EP | disclosed |
| EP-3583092-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-05-26 | — | — | EP | disclosed |