SCHEMBL23396388

SCHEMBL23396388

CCc1cnc(-c2cc(OC[C@H]3CCOC3)cc(C(=O)NCc3cnc(C)cn3)c2)s1

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 20/20 0.85
P2RX2 Q9UBL9 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23396399 1.00 P2RX3 (0.85) P2RX3P2RX2
SCHEMBL23396389 1.00 P2RX3 (0.85) P2RX3P2RX2
SCHEMBL29441114 0.92 P2RX3 (1.00) P2RX3P2RX2
SCHEMBL19950221 0.92 P2RX3 (1.00) P2RX3P2RX2
SCHEMBL29441044 0.92 P2RX3 (1.00) P2RX3P2RX2
SCHEMBL17824261 0.92 P2RX3 (1.00) P2RX3P2RX2
SCHEMBL17823497 0.92 P2RX3 (1.00) P2RX3P2RX2
SCHEMBL23396298 0.89 P2RX3 (0.82) P2RX3P2RX2
SCHEMBL23396347 0.89 P2RX3 (0.82) P2RX3P2RX2
SCHEMBL23396117 0.89 P2RX3 (0.82) P2RX3P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3230281-B1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES BAYER AG (DE) 2021-05-26 EP disclosed