Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664780 | 0.77 | NPSR1 (0.46) | NPSR1TRPM8ALDH1A1NPC1POLB | |
| SCHEMBL17591554 | 0.75 | AKT1 (0.52) | AKT1NPSR1TRPM8TGM2ALDH1A1 | |
| SCHEMBL1629579 | 0.75 | TRPM8 (0.57) | AKT1NPSR1TRPM8TGM2ALDH1A1 | |
| SCHEMBL3239982 | 0.75 | NPSR1 (0.44) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL648421 | 0.74 | AKT1 (0.45) | AKT1NPSR1TRPM8TGM2ALDH1A1 | |
| SCHEMBL5774899 | 0.74 | NPSR1 (0.43) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL4681303 | 0.73 | HPGD (0.45) | ALDH1A1POLBHTTRAB9AGLA | |
| SCHEMBL7864460 | 0.72 | NPSR1 (0.46) | AKT1NPSR1TRPM8TGM2ALDH1A1 | |
| SCHEMBL6843946 | 0.72 | NPSR1 (0.64) | NPSR1TRPM8ALDH1A1NPC1POLB | |
| SCHEMBL6611167 | 0.72 | AKT1 (0.43) | AKT1NPSR1TRPM8TGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358845-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2011-08-24 | — | — | EP | claimed |
| WO-2010065406-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2010-06-10 | — | — | WO | claimed |