Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929807 | 1.00 | PDPK1 (0.43) | PDPK1CYP2A6LOXL2ADORA2AADORA1 | |
| SCHEMBL3788170 | 0.81 | PDPK1 (0.69) | PDPK1CYP2A6LOXL2ALDH1A1ADRB2 | |
| SCHEMBL102331 | 0.80 | PDPK1 (0.59) | PDPK1CYP2A6LOXL2ADORA2AADORA1 | |
| SCHEMBL18656772 | 0.79 | ADORA2A (0.33) | PDPK1CYP2A6ADORA2AADORA1ADORA3 | |
| SCHEMBL5647065 | 0.78 | ADORA2A (0.42) | PDPK1CYP2A6LOXL2ADORA2AADORA1 | |
| SCHEMBL1763565 | 0.78 | PDPK1 (0.41) | PDPK1CYP2A6LOXL2ADORA2AADORA1 | |
| SCHEMBL2629268 | 0.78 | ADORA2A (0.45) | PDPK1CYP2A6LOXL2ADORA2AADORA1 | |
| SCHEMBL13191731 | 0.78 | PDPK1 (0.41) | PDPK1CYP2A6LOXL2ADORA2AADORA1 | |
| SCHEMBL28570271 | 0.78 | PDPK1 (0.41) | PDPK1CYP2A6LOXL2ADORA2AADORA1 | |
| SCHEMBL31556353 | 0.77 | PDPK1 (0.56) | PDPK1CYP2A6LOXL2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361444-A1 | MATERIALS | Lomox Limited (GB) | 2011-08-31 | — | — | EP | disclosed |
| WO-2009103952-A1 | MATERIALS | LOMOX LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |