Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 7/20 | 0.33 |
| ▸ | CA2 | P00918 | 6/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2339827 | 1.00 | F2 (0.50) | F2PRSS1PRSS2PRSS3CA12 | |
| SCHEMBL446590 | 0.83 | F2 (0.44) | F2PRSS1PRSS2PRSS3CA12 | |
| SCHEMBL2615565 | 0.82 | F2 (0.43) | F2PRSS1PRSS2PRSS3CA12 | |
| SCHEMBL15893686 | 0.82 | F2 (0.43) | F2PRSS1PRSS2PRSS3CA12 | |
| SCHEMBL2369612 | 0.78 | F2 (0.40) | F2PRSS1PRSS2PRSS3CA12 | |
| SCHEMBL2369616 | 0.78 | F2 (0.40) | F2PRSS1PRSS2PRSS3CA12 | |
| SCHEMBL16298358 | 0.78 | F2 (0.40) | F2PRSS1PRSS2PRSS3CA12 | |
| SCHEMBL14493144 | 0.77 | F2 (0.39) | F2PRSS1PRSS2PRSS3CA12 | |
| SCHEMBL7370215 | 0.76 | F2 (0.56) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL29539627 | 0.75 | F2 (0.44) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498723-A1 | NEW EFFECTIVE AMINOGLYCOSIDE ANTIBIOTIC FOR MULTIDRUG-RESISTANT BACTERIA | Microbial Chemistry Research Foundation (JP) | 2019-06-19 | — | — | EP | disclosed |
| WO-2017032892-A1 | 1,7-DIARYL-1,6-HEPTADIENE-3,5-DIONE DERIVATIVES, METHODS FOR THE PRODCUTION AND USE THEREOF | UNIVERSITÄTSKLINIKUM REGENSBURG (DE) | 2017-03-02 | — | — | WO | disclosed |
| EP-3018125-A1 | NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR | Shin Nippon Biomedical Laboratories, Ltd. (JP) | 2016-05-11 | — | — | EP | disclosed |
| EP-2534138-A1 | 1,2,3-TRIAZOLE-BASED PEPTIDOMIMETIC INTEGRIN INHIBITORS FOR THE DIAGNOSIS AND THERAPY OF TUMORS | Universita' Degli Studi di Firenze (IT) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011098603-A1 | 1,2,3-TRIAZOLE-BASED PEPTIDOMIMETIC INTEGRIN INHIBITORS FOR THE DIAGNOSIS AND THERAPY OF TUMORS | UNIVERSITA' DEGLI STUDI DI FIRENZE (IT) | 2011-08-18 | — | — | WO | disclosed |
| WO-2002014349-A2 | NON-COVALENT INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION | CORVAS INTERNATIONAL, INC. (US) | 2002-02-21 | — | — | WO | disclosed |