SCHEMBL446590

SCHEMBL446590

CC(C)(C)OC(=O)NC(=NS(=O)(=O)C(F)(F)F)NC(=O)OC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.44
PRSS1 P07477 2/20 0.44
PRSS2 P07478 2/20 0.44
PRSS3 P35030 2/20 0.44
CA1 P00915 6/20 0.35
CA2 P00918 5/20 0.35
CA12 O43570 4/20 0.35
CA14 Q9ULX7 4/20 0.35
CA7 P43166 3/20 0.35
APLNR P35414 1/20 0.32
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2369612 0.94 F2 (0.40) F2PRSS1PRSS2PRSS3CA1
SCHEMBL2369616 0.94 F2 (0.40) F2PRSS1PRSS2PRSS3CA1
SCHEMBL14493144 0.92 F2 (0.39) F2PRSS1PRSS2PRSS3CA1
SCHEMBL16298358 0.91 F2 (0.40) F2PRSS1PRSS2PRSS3CA1
SCHEMBL24927874 0.89 F2 (0.36) F2PRSS1PRSS2PRSS3CA1
SCHEMBL15893686 0.85 F2 (0.43) F2PRSS1PRSS2PRSS3CA1
SCHEMBL2615565 0.85 F2 (0.43) F2PRSS1PRSS2PRSS3CA1
SCHEMBL2339827 0.83 F2 (0.50) F2PRSS1PRSS2PRSS3CA1
SCHEMBL2339824 0.83 F2 (0.50) F2PRSS1PRSS2PRSS3CA1
SCHEMBL13583119 0.83 EPHX1 (0.41) CA1CA2CA12CA14CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 688 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117352668-A Preparation method of pyrophosphate secondary battery positive electrode material with high air stability 深圳珈钠能源科技有限公司 2024-01-05 CN claimed
WO-2004093821-A2 TREATMENT OF ANTHRAX INFECTION USING INHIBITORS OF LETHAL FACTOR PROTEASE ACTIVITY HAWAII BIOTECH, INC. (US) 2004-11-04 WO claimed
US-20030232974-A1 Guanidinylation, guanidinoglycosides, uses, and methods of assaying their activity THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-12-18 US claimed
US-20030055214-A1 Guanidinylation reagents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-03-20 US claimed
EP-0983232-B1 GUANIDINYLATION REAGENTS UNIV CALIFORNIA (US) 2002-11-13 EP claimed
US-6072075-A Guanidinylation reagents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-06-06 US claimed
EP-0983232-A2 GUANIDINYLATION REAGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-03-08 EP claimed
WO-1998052917-A2 GUANIDINYLATION REAGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-11-26 WO claimed
US-12636386-B2 Compositions and methods for the treatment and imaging of cancer BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2026-05-26 US disclosed
WO-2026087442-A1 AMINO-IMIDAZOLE ANTIBACTERIAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
EP-4724456-A1 STEROL-BASED CATIONIC LIPIDS WITH AROMATIC HEAD GROUPS Sanofi (FR) 2026-04-15 EP disclosed
US-12594275-B2 Immunophilin binding agents and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-04-07 US disclosed
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-19 US disclosed
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-12 US disclosed
EP-1182207-A2 Non-covalent inhibitors of urokinase and blood vessel formation CORVAS INTERNATIONAL, INC. (US) 2002-02-27 EP disclosed
EP-1040094-A1 SUBSTITUTED CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARMACEUTICALS INC. (US) 2000-10-04 EP disclosed
US-6072075-A Guanidinylation reagents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-06-06 US disclosed
EP-0983232-A2 GUANIDINYLATION REAGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-03-08 EP disclosed
WO-1999033781-A1 SUBSTITUTED CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARMACEUTICALS, INC. (US) 1999-07-08 WO disclosed
WO-1998052917-A2 GUANIDINYLATION REAGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232974-A1 Guanidinylation, guanidinoglycosides, uses, and methods of assaying their activity GMPS, GDA, RNGTT F2 4314/4885PRSS1 949/4885PRSS2 1005/4885
US-12594275-B2 Immunophilin binding agents and uses thereof CCR1, CCRL2, CCR3 F2 2252/4885PRSS1 3959/4885PRSS2 4487/4885
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PHOSPHO1, LIPC, SDCBP F2 4863/4885PRSS1 3497/4885PRSS2 4483/4885
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS SIN3A, PLIN3, MSR1 F2 4766/4885PRSS1 4481/4885PRSS2 4623/4885
US-12636386-B2 Compositions and methods for the treatment and imaging of cancer GBA1, GALC, CD47 F2 2597/4885PRSS1 3241/4885PRSS2 4046/4885
US-20030055214-A1 Guanidinylation reagents GDA, GMPS, GNMT F2 4797/4885PRSS1 3126/4885PRSS2 2179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.