SCHEMBL23398443

SCHEMBL23398443

CCCCc1c(O)c(-c2ccc(C)cc2)nn1CC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
ESR1 P03372 4/20 0.39
TP53 P04637 1/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
HTT P42858 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
HSD11B1 P28845 1/20 0.35
TLR8 Q9NR97 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400467 0.91 ESR1 (0.44) MEN1KMT2AESR1TP53ALDH1A1
SCHEMBL23398824 0.91 ESR1 (0.44) MEN1KMT2AESR1TP53ALDH1A1
SCHEMBL23402624 0.91 ESR1 (0.40) MEN1KMT2AESR1TP53ALDH1A1
SCHEMBL23399425 0.87 MEN1 (0.46) MEN1KMT2AESR1MAPTSMN1; SMN2
SCHEMBL23402320 0.87 SMN1; SMN2 (0.37) MEN1KMT2AESR1TP53ALDH1A1
SCHEMBL23398724 0.87 MEN1 (0.38) MEN1KMT2AESR1TP53ALDH1A1
SCHEMBL23399693 0.86 ESR1 (0.44) MEN1KMT2AESR1TP53ALDH1A1
SCHEMBL23403107 0.85 RAB9A (0.40) MEN1KMT2AESR1TP53ALDH1A1
SCHEMBL23400510 0.83 ESR1 (0.44) MEN1KMT2AESR1TP53ALDH1A1
SCHEMBL23398605 0.82 ESR1 (0.46) MEN1KMT2AESR1TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed