SCHEMBL23398491

SCHEMBL23398491

CCCn1nc(C)c(-c2ccccc2)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.48
POLB P06746 2/20 0.48
MAPT P10636 4/20 0.46
CDK8 P49336 1/20 0.42
ACVR1 Q04771 1/20 0.42
RAB9A P51151 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ESR1 P03372 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
TSHR P16473 2/20 0.41
KDM4E B2RXH2 2/20 0.41
CRHBP P24387 1/20 0.41
MAPK1 P28482 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
CRHR2 Q13324 1/20 0.41
NR1H3 Q13133 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400686 0.91 NR1H3 (0.52) GAAPOLBMAPTCDK8ACVR1
SCHEMBL23399897 0.87 ADORA2A (0.40) GAAPOLBMAPTKMT2AESR1
SCHEMBL23401645 0.87 GAA (0.50) GAAPOLBMAPTCDK8ACVR1
SCHEMBL23398438 0.86 DHFR (0.43) GAAMAPTMEN1KMT2AESR1
SCHEMBL23402700 0.84 MEN1 (0.51) GAAMAPTMEN1KMT2AESR1
SCHEMBL23400425 0.81 KMT2A (0.40) GAAMAPTRAB9AMEN1KMT2A
SCHEMBL23400518 0.81 ESR1 (0.49) GAAPOLBMAPTRAB9AMEN1
SCHEMBL23401922 0.81 ESR1 (0.49) GAAPOLBMAPTRAB9AMEN1
SCHEMBL23403417 0.80 KDM4E (0.42) GAAPOLBMAPTMEN1KMT2A
SCHEMBL23400655 0.79 GAA (0.47) GAAPOLBMAPTCDK8ACVR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed