SCHEMBL23398494

SCHEMBL23398494

Cc1ccc(-n2[nH]cc(-c3ccccc3C)c2=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
MEN1 O00255 7/20 0.47
KMT2A Q03164 7/20 0.47
GAA P10253 4/20 0.47
NPC1 O15118 4/20 0.47
ALDH1A1 P00352 2/20 0.46
VHL P40337 1/20 0.45
TP53 P04637 1/20 0.43
BRD4 O60885 1/20 0.41
DDAH1 O94760 1/20 0.39
RAB9A P51151 3/20 0.39
PKM P14618 1/20 0.39
POLB P06746 1/20 0.37
TLR9 Q9NR96 1/20 0.37
MITF O75030 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401887 0.90 GAA (0.56) MAPTMEN1KMT2AGAANPC1
SCHEMBL23398776 0.84 MAPT (0.50) MAPTMEN1KMT2AGAANPC1
SCHEMBL23399696 0.83 GAA (0.63) MAPTMEN1KMT2AGAANPC1
SCHEMBL23403074 0.81 VHL (0.47) MAPTMEN1KMT2AGAANPC1
SCHEMBL23402975 0.80 MEN1 (0.59) MAPTMEN1KMT2AGAANPC1
SCHEMBL23400092 0.79 GAA (0.72) MAPTMEN1KMT2AGAANPC1
SCHEMBL23400677 0.78 ALDH1A1 (0.54) MAPTMEN1KMT2AGAANPC1
SCHEMBL23399068 0.76 MEN1 (0.59) MAPTMEN1KMT2AGAANPC1
SCHEMBL23402681 0.75 BRD4 (0.50) MAPTMEN1KMT2ANPC1ALDH1A1
SCHEMBL10738689 0.75 VHL (0.78) MAPTGAAVHLTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed