Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23402423 | 0.92 | NR1H3 (0.39) | ESR1SLC9A1TRPM8TLR8TSHR | |
| SCHEMBL23402803 | 0.90 | ESR1 (0.40) | ESR1PTGS2SLC9A1TRPM8KDM4E | |
| SCHEMBL23400319 | 0.89 | ESR1 (0.40) | ESR1PTGS2SLC9A1TRPM8KDM4E | |
| SCHEMBL23400474 | 0.88 | TRPM8 (0.39) | SLC9A1TRPM8KDM4EHSD17B10POLB | |
| SCHEMBL23402998 | 0.87 | ESR1 (0.36) | ESR1PTGS2SLC9A1TRPM8KDM4E | |
| SCHEMBL23401437 | 0.85 | ESR1 (0.40) | ESR1PTGS2SLC9A1TRPM8TLR8 | |
| SCHEMBL23402901 | 0.85 | TRPM8 (0.38) | ESR1TRPM8KDM4EHSD17B10TLR8 | |
| SCHEMBL23402177 | 0.83 | TRPM8 (0.34) | TRPM8KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL23402949 | 0.83 | NR1H3 (0.39) | ESR1SLC9A1KDM4ETLR8MAPT | |
| SCHEMBL23400511 | 0.81 | MEN1 (0.43) | ESR1SLC9A1CNR1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |