SCHEMBL23398641

SCHEMBL23398641

CCCCn1nc(O)c(CCC)c1-c1cccc(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.43
KDM4E B2RXH2 1/20 0.41
TLR8 Q9NR97 1/20 0.39
NR1H3 Q13133 1/20 0.39
CTSS P25774 1/20 0.38
CTSK P43235 1/20 0.38
ESR1 P03372 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.36
MAPT P10636 2/20 0.36
THRB P10828 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.36
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
TSHR P16473 1/20 0.35
ICMT O60725 3/20 0.34
NPC1 O15118 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SIRT2 Q8IXJ6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402527 0.96 TP53 (0.43) TP53KDM4ETLR8NR1H3CTSS
SCHEMBL23399469 0.92 CTSS (0.40) TP53KDM4ETLR8CTSSCTSK
SCHEMBL23399738 0.91 TP53 (0.43) TP53KDM4ETLR8NR1H3CTSS
SCHEMBL23398542 0.91 TP53 (0.43) TP53KDM4ETLR8NR1H3CTSS
SCHEMBL23403262 0.88 NPC1 (0.43) TP53KDM4ETLR8CTSSCTSK
SCHEMBL23401397 0.87 NPC1 (0.42) TP53KDM4ETLR8CTSSCTSK
SCHEMBL23399711 0.87 TP53 (0.40) TP53KDM4ETLR8NR1H3ESR1
SCHEMBL23399614 0.86 TP53 (0.45) TP53KDM4ETLR8NR1H3ESR1
SCHEMBL23400887 0.85 NR1H3 (0.47) NR1H3ESR1MAPTMEN1KMT2A
SCHEMBL23400272 0.84 CTSS (0.41) TP53KDM4ETLR8CTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed