Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2339564 | 1.00 | STS (0.51) | STSPIK3CDTACR1USP30PIK3CA | |
| SCHEMBL22694519 | 0.91 | STS (0.43) | STSPIK3CDTACR1USP30PIK3CA | |
| SCHEMBL14848764 | 0.89 | MAPT (0.44) | STSPIK3CDTACR1USP30PIK3CA | |
| SCHEMBL18615672 | 0.86 | PDE4B (0.49) | STSPIK3CDTACR1USP30PIK3CA | |
| SCHEMBL4877902 | 0.86 | PDE4B (0.49) | STSPIK3CDTACR1USP30PIK3CA | |
| SCHEMBL18615447 | 0.86 | PDE4B (0.49) | STSPIK3CDTACR1USP30PIK3CA | |
| SCHEMBL24566840 | 0.85 | USP30 (0.48) | STSPIK3CDTACR1USP30PIK3CA | |
| SCHEMBL29839800 | 0.85 | USP30 (0.48) | STSPIK3CDTACR1USP30PIK3CA | |
| SCHEMBL29116269 | 0.85 | USP30 (0.48) | STSPIK3CDTACR1USP30PIK3CA | |
| SCHEMBL24566231 | 0.85 | USP30 (0.48) | STSPIK3CDTACR1USP30PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975262-B2 | Synthetic mimetics of host defense and uses thereof | CELLCEUTIX CORPORATION (US) | 2015-03-10 | — | — | US | claimed |
| US-20130090345-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | POLYMEDIX, INC. (US) | 2013-04-11 | — | — | US | claimed |
| US-8278309-B2 | Synthetic mimetics of host defense and uses thereof | POLYMEDIX, INC. (US) | 2012-10-02 | — | — | US | claimed |
| US-20100105703-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | POLYMEDIX, INC. (US) | 2010-04-29 | — | — | US | claimed |
| US-20230310435-A1 | HOST DEFENSE PROTEIN (HDP) MIMETICS FOR PROPHYLAXIS AND/OR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT | INNOVATION PHARMACEUTICALS INC. (US) | 2023-10-05 | — | — | US | disclosed |
| US-11666571-B2 | Host defense protein (HDP) mimetics for prophylaxis and/or treatment of inflammatory diseases of the gastrointestinal tract | INNOVATION PHARMACEUTICALS INC. (US) | 2023-06-06 | — | — | US | disclosed |
| EP-3258927-B1 | HOST DEFENSE PROTEIN (HDP) MIMETICS FOR PROPHYLAXIS AND/OR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT | INNOVATION PHARMACEUTICALS INC (US) | 2021-06-09 | — | — | EP | disclosed |
| US-20200368232-A1 | Host Defense Protein (HDP) Mimetics For Prophylaxis And/Or Treatment Of Inflammatory Diseases Of The Gastrointestinal Tract | INNOVATION PHARMACEUTICALS INC. (US) | 2020-11-26 | — | — | US | disclosed |
| US-20160243117-A1 | Host Defense Protein (HDP) Mimetics For Prophylaxis And/Or Treatment Of Inflammatory Diseases Of The Gastrointestinal Tract | CELLCEUTIX CORPORATION (US) | 2016-08-25 | — | — | US | disclosed |
| US-8975262-B2 | Synthetic mimetics of host defense and uses thereof | CELLCEUTIX CORPORATION (US) | 2015-03-10 | — | — | US | disclosed |
| US-20130090345-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | POLYMEDIX, INC. (US) | 2013-04-11 | — | — | US | disclosed |
| US-8278309-B2 | Synthetic mimetics of host defense and uses thereof | POLYMEDIX, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| EP-2358380-A1 | SYNTHETIC MIMETICS OF HOST DEFENSE AND USES THEREOF | Polymedix, Inc. (US) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010062573-A1 | SYNTHETIC MIMETICS OF HOST DEFENSE AND USES THEREOF | POLYMEDIX, INC. (US) | 2010-06-03 | — | — | WO | disclosed |
| US-20100105703-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | POLYMEDIX, INC. (US) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200368232-A1 | Host Defense Protein (HDP) Mimetics For Prophylaxis And/Or Treatment Of Inflammatory Diseases Of The Gastrointestinal Tract | FABP2, HMGB1, MASP2 | STS 3678/4885PIK3CD 4510/4885TACR1 1060/4885 |
| US-11666571-B2 | Host defense protein (HDP) mimetics for prophylaxis and/or treatment of inflammatory diseases of the gastrointestinal tract | FABP2, HMGB1, MASP2 | STS 3678/4885PIK3CD 4510/4885TACR1 1060/4885 |
| US-20130090345-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | TLR3, MYD88, TLR5 | STS 2870/4885PIK3CD 3897/4885TACR1 3382/4885 |
| US-20160243117-A1 | Host Defense Protein (HDP) Mimetics For Prophylaxis And/Or Treatment Of Inflammatory Diseases Of The Gastrointestinal Tract | FABP2, HMGB1, MASP2 | STS 3678/4885PIK3CD 4510/4885TACR1 1060/4885 |
| US-20100105703-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | TLR3, MYD88, TLR5 | STS 2870/4885PIK3CD 3897/4885TACR1 3382/4885 |
| US-20230310435-A1 | HOST DEFENSE PROTEIN (HDP) MIMETICS FOR PROPHYLAXIS AND/OR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT | FABP2, HMGB1, MASP2 | STS 3678/4885PIK3CD 4510/4885TACR1 1060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.