SCHEMBL23398762

SCHEMBL23398762

CCCn1nc(C)c(O)c1C

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 3/20 0.46
ADORA2B P29275 3/20 0.46
GLS O94925 1/20 0.38
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.36
ESR1 P03372 2/20 0.33
LMNA P02545 2/20 0.33
ALOX15 P16050 1/20 0.33
GAA P10253 2/20 0.32
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
APAF1 O14727 1/20 0.31
HPGD P15428 1/20 0.31
CYP1A1 P04798 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23398731 0.88 HPGD (0.38) ADORA2AADORA2BGLSALDH1A1POLB
SCHEMBL9950753 0.82 LMNA (0.45) ADORA2AADORA2BGLSALDH1A1LMNA
SCHEMBL23402368 0.79 ADORA2A (0.43) ADORA2AADORA2BPOLBESR1
SCHEMBL23403211 0.79 ADORA2A (0.43) ADORA2AADORA2BPOLBESR1
SCHEMBL23401073 0.79 ADORA2A (0.35) ADORA2AADORA2BPOLBESR1GAA
SCHEMBL23399385 0.78 ADORA2A (0.34) ADORA2AADORA2BPOLBESR1
SCHEMBL23402455 0.76 ADORA2A (0.41) ADORA2AADORA2BALDH1A1ESR1LMNA
SCHEMBL23398445 0.76 ADORA2A (0.41) ADORA2AADORA2BESR1
SCHEMBL23400028 0.76 ADORA2A (0.44) ADORA2AADORA2BESR1APAF1
SCHEMBL23403023 0.76 CNR1 (0.35) ADORA2AADORA2BPOLBESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed