SCHEMBL23399016

SCHEMBL23399016

Cc1ccc(-n2nc(O)cc2-c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
CYP2C9 P11712 2/20 0.53
ALDH1A1 P00352 3/20 0.52
HPGD P15428 2/20 0.52
PPP1CA P62136 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
RPA1 P27694 3/20 0.50
ALOX5 P09917 1/20 0.50
PTGS2 P35354 2/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
RECQL P46063 1/20 0.47
PTGS1 P23219 1/20 0.46
SMPD1 P17405 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400981 0.94 NPC1 (0.58) NPC1RAB9ACYP2C9ALDH1A1HPGD
SCHEMBL23401943 0.92 SMN1; SMN2 (0.55) NPC1RAB9ACYP2C9PPP1CASMN1; SMN2
SCHEMBL8019126 0.88 NPC1 (0.62) NPC1RAB9AALDH1A1HPGDRPA1
SCHEMBL23400583 0.88 L3MBTL1 (0.54) NPC1RAB9ACYP2C9ALDH1A1HPGD
SCHEMBL23398739 0.84 RPA1 (0.57) NPC1RAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL23400539 0.84 RPA1 (0.68) NPC1RAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL13495159 0.84 MALT1 (0.59) NPC1RAB9APPP1CASMN1; SMN2RPA1
SCHEMBL10194259 0.83 NPC1 (0.83) NPC1RAB9ACYP2C9ALDH1A1HPGD
SCHEMBL23399947 0.83 RPA1 (0.69) NPC1RAB9ACYP2C9RPA1PTGS2
SCHEMBL27741431 0.83 FABP3 (0.52) NPC1RAB9ACYP2C9ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed