Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 11/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23401175 | 0.93 | TLR8 (0.40) | TLR8TP53KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL23402944 | 0.87 | SMN1; SMN2 (0.39) | TLR8TP53POLBSMN1; SMN2TDP2 | |
| SCHEMBL23400543 | 0.87 | TLR8 (0.43) | TLR8TP53ADORA3ADORA2AICMT | |
| SCHEMBL23400604 | 0.87 | TLR8 (0.43) | TLR8TP53ADORA3ADORA2AICMT | |
| SCHEMBL23398972 | 0.86 | SMN1; SMN2 (0.47) | POLBSMN1; SMN2HSD11B1 | |
| SCHEMBL23400538 | 0.85 | TLR8 (0.41) | TLR8TP53ADORA3ADORA2AICMT | |
| SCHEMBL23398610 | 0.84 | SRC (0.46) | TLR8TP53ADORA3ADORA2AICMT | |
| SCHEMBL23400291 | 0.83 | ALDH1A1 (0.44) | TLR8TP53ADORA3ADORA2AKDM4E | |
| SCHEMBL23399530 | 0.83 | RIPK2 (0.49) | TLR8TP53ADORA3ADORA2AICMT | |
| SCHEMBL23399773 | 0.83 | SMN1; SMN2 (0.43) | TLR8TP53ADORA3ADORA2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |