SCHEMBL23399144

SCHEMBL23399144

CCCCn1ncc(O)c1-c1cccc(C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.45
KDM4E B2RXH2 1/20 0.43
TLR8 Q9NR97 1/20 0.41
NR1H3 Q13133 1/20 0.39
PTGIR P43119 2/20 0.38
TSHR P16473 1/20 0.37
GRIN2B Q13224 2/20 0.37
GRIN1 Q05586 1/20 0.37
ICMT O60725 2/20 0.36
SIGMAR1 Q99720 1/20 0.36
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
NFKB1 P19838 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SIRT2 Q8IXJ6 1/20 0.35
SLC9A1 P19634 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402596 0.92 TP53 (0.41) TP53KDM4ETLR8GRIN2BGRIN1
SCHEMBL23402196 0.86 NPC1 (0.41) TP53TLR8GRIN2BGRIN1SIGMAR1
SCHEMBL23399766 0.84 PTGIR (0.51) NR1H3PTGIRTSHRSLC9A1MEN1
SCHEMBL23402653 0.83 PTGIR (0.38) TP53TLR8NR1H3PTGIRTSHR
SCHEMBL23400329 0.81 TLR8 (0.44) TP53KDM4ETLR8NR1H3PTGIR
SCHEMBL23398387 0.80 GRIN2B (0.37) TP53TLR8GRIN2BGRIN1ICMT
SCHEMBL23402534 0.80 TP53 (0.46) TP53KDM4ETLR8NR1H3TSHR
SCHEMBL23399614 0.78 TP53 (0.45) TP53KDM4ETLR8NR1H3TSHR
SCHEMBL23400529 0.78 PRMT5 (0.43) KDM4ETLR8NPC1RAB9AMAPT
SCHEMBL23399131 0.77 TP53 (0.47) TP53KDM4ETLR8NR1H3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed