SCHEMBL23402196

SCHEMBL23402196

CCn1ncc(O)c1-c1cccc(C)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GRIN2B Q13224 4/20 0.39
GRIN1 Q05586 3/20 0.39
TRPM8 Q7Z2W7 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TLR8 Q9NR97 1/20 0.37
TP53 P04637 1/20 0.37
EGLN1 Q9GZT9 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
TRPV1 Q8NER1 1/20 0.37
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
IDO1 P14902 1/20 0.36
METAP2 P50579 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
NR3C1 P04150 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402596 0.88 TP53 (0.41) GRIN2BGRIN1ALDH1A1TLR8TP53
SCHEMBL23399144 0.86 TP53 (0.45) NPC1GRIN2BGRIN1ALDH1A1TLR8
SCHEMBL23398387 0.84 GRIN2B (0.37) NPC1GRIN2BGRIN1TLR8TP53
SCHEMBL23401725 0.84 IDO1 (0.42) GRIN2BIDO1
SCHEMBL23400670 0.82 PTGIR (0.42) NPC1L3MBTL1ALDH1A1RAB9AKMT2A
SCHEMBL23399837 0.81 KIF11 (0.42) GRIN2BGRIN1ALDH1A1KMT2AHDAC8
SCHEMBL23400886 0.81 CTSS (0.41)
SCHEMBL23403361 0.81 CYP11B2 (0.40) NPC1ALDH1A1
SCHEMBL23400529 0.80 PRMT5 (0.43) NPC1L3MBTL1ALDH1A1TLR8RAB9A
SCHEMBL23402753 0.79 NPC1 (0.46) NPC1L3MBTL1GRIN2BGRIN1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed