SCHEMBL23399274

SCHEMBL23399274

CCCc1nn(Cc2ccccc2)c(CCC)c1O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 1/20 0.42
PTGDR2 Q9Y5Y4 6/20 0.41
PDE4A P27815 2/20 0.41
PDE4B Q07343 2/20 0.41
PDE4C Q08493 2/20 0.41
PDE4D Q08499 2/20 0.41
CYP19A1 P11511 1/20 0.40
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402702 0.81 PTGDR2 (0.51) ALDH1A1PTGDR2POLBKDM4E
SCHEMBL23399061 0.77 ADORA2A (0.32)
SCHEMBL23398746 0.77 SMN1; SMN2 (0.31)
SCHEMBL23401002 0.75 USP2 (0.46) KMT2AALDH1A1POLBGAAKDM4E
SCHEMBL8900910 0.74 ALDH1A1 (0.47) KMT2AALDH1A1PDE4APDE4BPDE4C
SCHEMBL23400358 0.74 TSHR (0.46) KMT2AALDH1A1CYP19A1GAAKDM4E
SCHEMBL30728962 0.74 SLC16A3 (0.55) KMT2AALDH1A1PDE4APDE4BPDE4C
SCHEMBL23402189 0.74 MAPT (0.43) KMT2AALDH1A1PDE4APDE4BPDE4C
SCHEMBL23398479 0.74 ESR1 (0.33)
SCHEMBL176993 0.73 SLC16A3 (0.46) ALDH1A1PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed