SCHEMBL23399298

SCHEMBL23399298

CCCn1nc(-c2cccc(C)c2)c(-c2ccc(C)cc2)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.43
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TLR8 Q9NR97 1/20 0.38
HEXA P06865 1/20 0.36
HEXB P07686 1/20 0.36
TP53 P04637 2/20 0.36
GRIA2 P42262 1/20 0.35
GRIA4 P48058 1/20 0.35
MITF O75030 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
CRHBP P24387 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401406 0.94 ESR1 (0.44) ESR1MEN1KMT2AL3MBTL1CYP1A2
SCHEMBL23402459 0.93 ESR1 (0.42) ESR1MEN1KMT2ACYP1A2TLR8
SCHEMBL23399866 0.90 MEN1 (0.40) MEN1KMT2AL3MBTL1CYP1A2CYP2C19
SCHEMBL23400518 0.88 ESR1 (0.49) ESR1MEN1KMT2ACYP2C9CYP2C19
SCHEMBL23401922 0.88 ESR1 (0.49) ESR1MEN1KMT2ACYP2C9CYP2C19
SCHEMBL23399168 0.88 ESR1 (0.47) ESR1MEN1KMT2ATP53MAPT
SCHEMBL23398858 0.86 NR1H3 (0.45) ESR1MEN1KMT2AL3MBTL1CYP1A2
SCHEMBL23399081 0.84 ESR1 (0.44) ESR1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL23401249 0.84 KMT2A (0.37) MEN1KMT2AL3MBTL1POLBICMT
SCHEMBL23401101 0.82 L3MBTL1 (0.42) MEN1KMT2AL3MBTL1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed