SCHEMBL23399646

SCHEMBL23399646

CCCCn1c(=O)c(N)c(C)n1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.56
BCHE P06276 1/20 0.56
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
POLB P06746 1/20 0.46
ALOX15 P16050 2/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.41
ADORA3 P0DMS8 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 2/20 0.40
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
PGR P06401 1/20 0.40
RORA P35398 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403330 0.91 BCHE (0.59) PTGS2BCHEKMT2AMEN1NPSR1
SCHEMBL23400266 0.88 PTGS2 (0.60) PTGS2BCHEKMT2AMEN1NPSR1
SCHEMBL23400232 0.84 BCHE (0.58) PTGS2BCHEKMT2AMEN1NPSR1
SCHEMBL23400033 0.84 PTGS2 (0.44) PTGS2BCHEKMT2AMEN1NPSR1
SCHEMBL23401360 0.83 BCHE (0.43) PTGS2BCHEKMT2AMEN1NPSR1
SCHEMBL23401295 0.82 BCHE (0.42) PTGS2BCHEKMT2AMEN1NPSR1
SCHEMBL17035227 0.79 BCHE (0.64) PTGS2BCHEKMT2AMEN1NPSR1
SCHEMBL23401471 0.79 BCHE (0.55) PTGS2BCHEKMT2AMEN1NPSR1
SCHEMBL23400664 0.78 BCHE (0.54) PTGS2BCHEKMT2AMEN1NPSR1
SCHEMBL23403554 0.77 KMT2A (0.44) KMT2AMEN1NPSR1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed