SCHEMBL23399686

SCHEMBL23399686

CCCCc1c(O)nn(-c2ccc(C)cc2)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
RAB9A P51151 5/20 0.40
TP53 P04637 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
NPC1 O15118 4/20 0.38
MAPK1 P28482 3/20 0.38
KMT2A Q03164 3/20 0.38
NPSR1 Q6W5P4 3/20 0.38
NFKB1 P19838 2/20 0.38
MAPT P10636 2/20 0.38
TSHR P16473 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GMNN O75496 1/20 0.38
USP2 O75604 1/20 0.38
ESR1 P03372 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402509 0.92 KMT2A (0.44) ALDH1A1RAB9ATP53SMN1; SMN2LMNA
SCHEMBL23402151 0.88 NPC1 (0.51) RAB9ASMN1; SMN2LMNAHTTNPC1
SCHEMBL23398747 0.86 KMT2A (0.37) ALDH1A1RAB9ATP53SMN1; SMN2LMNA
SCHEMBL23403227 0.85 PDE4D (0.49) ALDH1A1RAB9ASMN1; SMN2LMNANPC1
SCHEMBL23400167 0.85 ALDH1A1 (0.43) ALDH1A1RAB9ATP53SMN1; SMN2LMNA
SCHEMBL23401674 0.85 MAPK1 (0.39) ALDH1A1RAB9ATP53SMN1; SMN2LMNA
SCHEMBL23402663 0.85 TP53 (0.36) ALDH1A1RAB9ATP53SMN1; SMN2LMNA
SCHEMBL23403174 0.84 MAPK1 (0.41) ALDH1A1RAB9ATP53SMN1; SMN2LMNA
SCHEMBL23403014 0.84 KMT2A (0.36) ALDH1A1RAB9ATP53SMN1; SMN2LMNA
SCHEMBL23402313 0.82 ALDH1A1 (0.42) ALDH1A1RAB9ATP53SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed