SCHEMBL23399690

SCHEMBL23399690

CCCn1nc(O)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 1/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPT P10636 3/20 0.44
CRHBP P24387 2/20 0.44
CRHR2 Q13324 2/20 0.44
TSHR P16473 2/20 0.44
MAPK1 P28482 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
CNR1 P21554 2/20 0.43
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
SLC9A1 P19634 1/20 0.39
ESR1 P03372 2/20 0.39
NR1H3 Q13133 1/20 0.38
CYP1A2 P05177 2/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401779 0.93 CNR1 (0.42) PTGIRMEN1KMT2AMAPTCRHBP
SCHEMBL23398644 0.93 CNR1 (0.42) PTGIRMEN1KMT2AMAPTCRHBP
SCHEMBL23402089 0.91 PTGIR (0.49) PTGIRMEN1KMT2AMAPTCRHBP
SCHEMBL23399495 0.87 TP53 (0.41) PTGIRMEN1KMT2AMAPTCRHBP
SCHEMBL23401930 0.87 HTR2A (0.47) PTGIRMEN1KMT2ACRHBPCRHR2
SCHEMBL23402997 0.86 ESR1 (0.38) PTGIRMEN1KMT2ACNR1KDM4E
SCHEMBL23401019 0.86 ESR1 (0.42) PTGIRMEN1KMT2AMAPTCRHBP
SCHEMBL23398372 0.84 NR1H3 (0.47) PTGIRMEN1KMT2AMAPTCRHBP
SCHEMBL23400439 0.84 ESR1 (0.42) MEN1KMT2AMAPTCRHBPCRHR2
SCHEMBL23401631 0.84 CNR1 (0.52) PTGIRMEN1KMT2AMAPTCRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed