SCHEMBL23399700

SCHEMBL23399700

Cc1ccc(-c2c(O)nn(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP1A2 P05177 1/20 0.49
NPC1 O15118 8/20 0.46
RAB9A P51151 8/20 0.46
SMN1; SMN2 Q16637 5/20 0.46
ALDH1A1 P00352 4/20 0.46
MAPT P10636 3/20 0.46
STAT1 P42224 1/20 0.46
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
CCNA2 P20248 1/20 0.42
CDK2 P24941 1/20 0.42
TP53 P04637 1/20 0.41
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
GRM5 P41594 1/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401405 1.00 CYP2C9 (0.49) CYP2C9CYP2C19CYP1A2NPC1RAB9A
SCHEMBL23398962 0.98 NPC1 (0.47) CYP2C9CYP2C19CYP1A2NPC1RAB9A
SCHEMBL23399105 0.97 CYP2C9 (0.46) CYP2C9CYP2C19CYP1A2NPC1RAB9A
SCHEMBL23400156 0.97 CYP2C9 (0.46) CYP2C9CYP2C19CYP1A2NPC1RAB9A
SCHEMBL23401180 0.95 CYP1A2 (0.47) CYP2C9CYP2C19CYP1A2NPC1RAB9A
SCHEMBL23403297 0.91 SMN1; SMN2 (0.42) CYP2C9CYP2C19CYP1A2NPC1RAB9A
SCHEMBL23399903 0.91 CYP2C9 (0.49) CYP2C9CYP2C19CYP1A2NPC1RAB9A
SCHEMBL23402024 0.90 RPA1 (0.48) CYP2C9CYP2C19CYP1A2NPC1RAB9A
SCHEMBL23399436 0.90 RPA1 (0.48) CYP2C9CYP2C19CYP1A2NPC1RAB9A
SCHEMBL23400330 0.90 ALDH1A1 (0.48) CYP2C9CYP2C19CYP1A2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed