SCHEMBL23399774

SCHEMBL23399774

Cc1cccc(-c2c(O)c(-c3ccccc3)nn2-c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
ALDH1A1 P00352 3/20 0.51
L3MBTL1 Q9Y468 3/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
RPA1 P27694 1/20 0.45
LMNA P02545 2/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
MAPT P10636 4/20 0.43
TP53 P04637 3/20 0.43
GRM5 P41594 1/20 0.43
PTGER1 P34995 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400235 0.96 NPC1 (0.48) NPC1RAB9AALDH1A1L3MBTL1NFKB1
SCHEMBL23399901 0.96 RPA1 (0.50) NPC1RAB9AALDH1A1L3MBTL1NFKB1
SCHEMBL23402862 0.94 KMT2A (0.49) NPC1RAB9AALDH1A1L3MBTL1NFKB1
SCHEMBL23400326 0.91 RPA1 (0.51) NPC1RAB9AALDH1A1L3MBTL1NFKB1
SCHEMBL23399208 0.90 KMT2A (0.50) NPC1RAB9AALDH1A1L3MBTL1NFKB1
SCHEMBL23399519 0.89 ALDH1A1 (0.47) NPC1RAB9AALDH1A1L3MBTL1NFKB1
SCHEMBL23399875 0.89 MAPT (0.49) NPC1RAB9AALDH1A1L3MBTL1NFKB1
SCHEMBL23398567 0.88 RPA1 (0.48) NPC1RAB9AALDH1A1L3MBTL1NFKB1
SCHEMBL23399959 0.88 RPA1 (0.48) NPC1RAB9AALDH1A1L3MBTL1NFKB1
SCHEMBL23401060 0.87 NPC1 (0.56) NPC1RAB9AALDH1A1L3MBTL1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed