SCHEMBL23399985

SCHEMBL23399985

CC(C)Cc1cnn(-c2ccccc2)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
NR4A3 Q92570 1/20 0.41
CYP2C9 P11712 2/20 0.40
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
SMO Q99835 1/20 0.40
CYP2C8 P10632 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
MAPK1 P28482 2/20 0.40
MAPT P10636 2/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 5/20 0.37
LMNA P02545 3/20 0.37
HPGD P15428 3/20 0.37
HTT P42858 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401626 0.86 HIF1A (0.39) GABRA1GABRB2CYP2C9CYP2C8HCAR2
SCHEMBL23402199 0.84 NPC1 (0.44) GABRA1GABRB2SMOMAPK1MAPT
SCHEMBL26329004 0.82 SMO (0.55) CYP2C9DRD2DRD4DRD3SMO
SCHEMBL23399486 0.81 NR4A3 (0.55) NR4A3DRD2DRD4DRD3SMO
SCHEMBL23398554 0.80 MEN1 (0.41) GABRA1GABRB2CYP2C9SMOMAPT
SCHEMBL23400693 0.79 ALDH1A1 (0.41) CYP2C9MAPK1MAPTNPC1RAB9A
SCHEMBL23402338 0.79 USP2 (0.47) NR4A3DRD2DRD4DRD3SMO
SCHEMBL23399392 0.77 NR4A3 (0.48) NR4A3CYP2C9CYP2C8HCAR2MAPK1
SCHEMBL26331616 0.77 SMN1; SMN2 (0.51) CYP2C9DRD2DRD4DRD3SMO
SCHEMBL23398637 0.76 NR4A3 (0.43) NR4A3DRD2DRD4DRD3SMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed